Summary
Overview
Work History
Education
Skills
Grants awarded
Teaching Experience
Conference presentations
Publications
Additional Training
Timeline
Generic
Lucía Lorenzi

Lucía Lorenzi

Bioinformatics Scientist
Barcelona

Summary

Bioinformatics Scientist with a strong foundation in molecular biology, specializing in genomics and epigenomics in the context of cancer research. Currently working under a Marie Skłodowska-Curie Postdoctoral Fellowship, focusing on long non-coding RNAs as drivers of stemness in hematopoietic stem cells and leukemia. Passionate about leveraging computational tools to uncover insights into gene regulation in human disease. Skilled in end-to-end data analysis, including data generation, processing, statistical evaluation, and visualization. Experienced in leading bioinformatics projects and providing clear, actionable interpretations of complex biological data. Known for effective communication, whether in concise day-to-day interactions or delivering well-structured presentations to diverse audiences. Actively seeking the next step in industry, aiming to contribute to the discovery of new drugs and therapeutic approaches to treat human disease.

Overview

2025
2025
years of professional experience
3
3
Languages

Work History

Postdoctoral Researcher

Josep Carreras Leukaemia Research Institute (IJC)
Badalona
1 2023 - Current
  • Research funded by a Marie Skłodowska-Curie Postdoctoral Fellowship on the identification and characterization of long non-coding RNAs as drivers of stemness in hematopoietic stem cells and leukemia.
  • Main supervisor: Sergi Cuartero. Co-supervisor: Anna Bigas.
  • Contributed equally with principal investigator in the conception of the project and experimental design.
  • Led the computational analyses, scientific reasoning and results generation and reporting.

Bioinformatics Scientist

Josep Carreras Leukaemia Research Institute (IJC)
03.2021 - 12.2022
  • Led bioinformatics analyses at the Transcriptional dynamics in leukemia lab.
  • Developed bioinformatics pipelines for the analysis of high-throughput sequencing data including RNA-seq, ChIP-seq, ATAC-seq and HiC.
  • Helped test and provide feedback for new institutional HPC infrastructure.

Predoctoral Researcher

Ghent University
09.2016 - 01.2021
  • Led computational analyses in the RNA Atlas project, aimed at constructing an extended and comprehensive map of the human transcriptome.
  • Implemented extensive RNA sequencing data analysis workflows, integrating public and custom algorithms to extract meaningful information from 12 TB of raw sequencing data, including small, polyA, and total RNA sequencing experiments.
  • Detected, annotated and functionally analyzed all types of RNA molecules, from protein-coding to small, circular and long non-coding RNAs.
  • Published work in peer-reviewed journals and presented findings in international conferences.

Education

Ph.D. - Health Sciences

Ghent University
Ghent, Belgium
04.2015 - 01.2017

Master of Science - Bioinformatics

National University of Rosario
Rosario, Argentina
04.2001 -

B.Sc. (Licenciatura) - Biotechnology

National University of Rosario
Rosario, Argentin
04.2008 - 01.2014

High School - Polytechnic

Instituto Politécnico Superior "General San Martín"
Rosario, Argentina
01.2005 - 01.2007

Skills

R

Bash

Python

Perl

Full experience in next generation sequencing data analysis

RNA biology

Big data analysis and machine learning

Cancer research

Metagenomics

Grants awarded

  • 2022, Marie Skłodowska-Curie Actions (MSCA) - European Postdoctoral Fellowship, European Union, StemLinc - Identification and characterization of long non-coding RNAs as drivers of stemness in hematopoietic stem cells and leukemia
  • 2022, Postdoctoral AECC 2022, Scientific Foundation of the Spanish Association Against Cancer (FC), Declined due to having received the MSCA Postdoctoral Fellowship
  • 2022, Juan de la Cierva aid - postdoctoral research training, Spanish State Research Agency, Declined due to having received the MSCA Postdoctoral Fellowship

Teaching Experience

2013-2015 Teaching assistant at Department of Organic Chemistry

National University of Rosario, Argentina. 

  • Involved in planning and design of experimental practical work and preparation of equipment and supplies for lab instruction.
  • Guided students during practical sessions and assisted them in troubleshooting lab and theoretical problems.


2017 Teaching assistant in Python practical sessions

Ghent University, Belgium.

  • Guided master students during Python hands-on sessions and assisted them in troubleshooting.


2018 Master thesis supervisor

Ghent University, Belgium.

  • Supervised student on Bioinformatics M.Sc. thesis.

Conference presentations

  • 03/01/20, BeSHG 2020. Genome for all?, 20th annual meeting of the Belgian Society of Human Genetics, Oral presentation, The RNA Atlas: a single nucleotide resolution map of the human transcriptome.
  • 10/01/19, The Non-Coding Genome, EMBL Heidelberg, Germany, Flash talk and poster presentation, The RNA atlas, a single nucleotide resolution map of the human transcriptome.
  • 06/01/19, RNA 2019, 24th Annual Meeting of the RNA Society, Krakow, Poland, Poster presentation, RNA Atlas: a nucleotide resolution map of the human transcriptome.
  • 03/01/19, OncoPoint 2019, Ghent, Belgium, Storm session presentation, RNA atlas: a nucleotide resolution map of the human transcriptome.
  • 07/01/18, ISMB 2018, 26th Conference on Intelligent Systems for Molecular Biology, Chicago, USA, Oral presentation, RNA Atlas: a nucleotide resolution map of the human transcriptome.
  • 03/01/18, Applied Bioinformatics in Life Sciences, Leuven, Belgium, Poster presentation, RNA atlas: a nucleotide resolution map of the human transcriptome.
  • 03/01/17, OncoPoint Symposium, Ghent, Belgium, Storm session presentation, RNA atlas: building the most complete human reference transcriptome.
  • 08/01/13, IX Argentinian Congress of General Microbiology, SAMIGE, Rosario, Argentina, Poster presentation, Study of gene expression using biosensors in the context of Salmonella infection: lipid metabolism.
  • 07/01/13, XV Giambiagi Winter School, Buenos Aires, Argentina, Poster presentation, Study of bacterial pathogens using green fluorescent protein-biosensors: Characterization of lipid metabolism during Salmonella infections.

Publications

  • 2021, The RNA Atlas expands the catalog of human non-coding RNAs., Lucía Lorenzi, Hua-Sheng Chiu, Francisco Ávila Cobos, et al., Nat Biotechnol, https://doi.org/10.1038/s41587-021-00936-1
  • 2019, Long noncoding RNA expression profiling in cancer: Challenges and opportunities., Lucía Lorenzi, Francisco Avila Cobos, Anneleen Decock, Celine Everaert, Hetty Helsmoortel, Steve Lefever, Karen Verboom, Pieter-Jan Volders, Frank Speleman, Jo Vandesompele, Pieter Mestdagh., Genes Chromosomes Cancer, 58, 4, 191-199, 10.1002/gcc.22709
  • 2017, The infectious intracellular lifestyle of Salmonella Enterica relies on the adaptation to nutritional conditions within the Salmonella-containing vacuole., Lautaro Diacovich, Lucía Lorenzi, Mauro Tomassetti, Stéphane Méresse & Hugo Gramajo., Virulence, 8, 6, 975-992, 10.1080/21505594.2016.1270493

Additional Training

  • 10/01/23, Systems biology: from large datasets to biological insight, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, UK
  • 04/01/20 - 06/30/20, Machine Learning with Python, Institute for Continuing Education in Science (ICES), Dr. Bart Van Rompaye
  • 06/01/19, Scientific Python, HPC-UGent and Laboratory for Chemical Technology (LCT), Prof. Geert Jan Bex (UHasselt, VSC)
  • 12/01/17, Effective Scientific Communication, Ghent University, Belgium, Jean-luc Doumont
  • 09/01/16 - 02/28/17, Statistical Genomics, Ghent University, Belgium, Lieven Clement

Timeline

Bioinformatics Scientist

Josep Carreras Leukaemia Research Institute (IJC)
03.2021 - 12.2022

Predoctoral Researcher

Ghent University
09.2016 - 01.2021

Ph.D. - Health Sciences

Ghent University
04.2015 - 01.2017

B.Sc. (Licenciatura) - Biotechnology

National University of Rosario
04.2008 - 01.2014

High School - Polytechnic

Instituto Politécnico Superior "General San Martín"
01.2005 - 01.2007

Master of Science - Bioinformatics

National University of Rosario
04.2001 -

Postdoctoral Researcher

Josep Carreras Leukaemia Research Institute (IJC)
1 2023 - Current
Lucía LorenziBioinformatics Scientist