Jordi Yang Zhou

• Reporting updates from preclinical and clinical trials in oncology and hematology with a particular focus on the Chinese medical regulatory market
• Biomarker specialist in immunology and hepatology

I participated in the review process of drafts submitted to the journal providing critical judgement to the novelty and quality of the content

Thesis title: Identification of innate immune components

as biomarkers of early liver inflammation

Relevant publications:

• Yang Zhou, Jordi, et al. (2022) Identification and Isolation of Type II NKT Cell Subsets in Human Blood and Liver. Frontiers in Immunology 2022 (13), p. 898473
• Glehr, Gunther, Riquelme, Paloma, Yang Zhou, Jordi, et al. (2022) External validation of biomarkers for immune-related adverse events after immune checkpoint inhibition. Frontiers in Immunology 13, p. 1011040
• Yang Zhou, Jordi (2023) Innate immunity and early liver inflammation. Frontiers in Immunology 14
• Kleber, Julia, Yang Zhou, Jordi, et al. (2023) Immune profile of patients with peritoneal carcinomatosis selected for CRS-HIPEC therapy. Cancer Immunology, Immunotherapy
• Yang Zhou, Jordi, et al. (2023) Case report: Predictability of clinical response and rejection risk after immune checkpoint inhibition in liver transplantation. Frontiers in Transplantation 2
• Inventor of a diagnosis kit for liver steatosis grade. Patent submitted

Relevant title: Strategies to overcome limitations in transduction efficiency using the Phage/AAV hybrid viral vector

Relevant publication:

• Yang Zhou, Jordi et al. (2020) Initial Steps for the Development of a Phage-Mediated Gene Replacement Therapy Using CRISPR-Cas9 Technology. Journal of Clinical Medicine, 9, 1498, doi:10.3390/jcm9051498
• Inventor of the superior generation of Phage/AAV hybrid viral vector. IP pending

Relevant title: Characterizing AIP pathogenic variants in vitro and in silico

Abstract publication:

• Yang Zhou, Jordi, et al. (2018) The half-life of different aryl hydrocarbon receptor interacting protein (AIP) variants and their significance on clinical phenotype. Endocrine Abstracts, 2018, 59 P127 | DOI: 10.1530/endoabs.59.P127
• Database developer: the AIP Locus-Specific database for clinical diagnosis

Relevant title: Characterization of Heteromeric Amino acid Transporter (HAT) in amino acid homeostasis